doi: 10.1007/BF01923050.
Effect of carbenoxolone on phosphodiesterase and prostaglandin synthetase activities
- PMID: 204509
- DOI: 10.1007/BF01923050
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Effect of carbenoxolone on phosphodiesterase and prostaglandin synthetase activities
Experientia.
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Abstract
Carbenoxolone inhibited in vitro cAMP and cGMP phosphodiesterases in a concentration-dependent and noncompetitive manner. Prostaglandin synthetase activity of rabbit kidney medulla was slightly stimulated by carbenoxolone 0.1--0.5 mM, but inhibited by higher concentrations.
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