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Review
. 2010 May;94(3):465-78.
doi: 10.1016/j.mcna.2010.02.003.

Cardiovascular consequences of obese and nonobese obstructive sleep apnea

Kannan Ramar  1 , Sean M Caples
Affiliations
Review

Cardiovascular consequences of obese and nonobese obstructive sleep apnea

Kannan Ramar et al. Med Clin North Am. 2010 May.

Abstract

Current evidence suggests a role for obstructive sleep apnea (OSA) in the development of cardiovascular disorders. However, obesity is an active confounder in this relationship. OSA and obesity share similar pathophysiologic mechanisms potentially leading to cardiovascular disorders. Presence of OSA in obese patients may further contribute to adverse cardiovascular outcomes when compared with each condition in isolation. In this review the authors explore the complex relationship between OSA and obesity (and nonobese subjects) in the development of cardiovascular disorders.

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Figures

Fig. 1
Fig. 1
The interaction between obesity and OSA, and its cardiovascular consequences. Note some of the similar pathogenetic mechanisms between OSA and obesity for cardiovascular consequences. Combination of OSA and obesity probably increases the risk for cardiovascular disorders.
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