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Review
. 2010 Mar;8(1):1-9.
doi: 10.1016/S1672-0229(10)60001-0.

Host proteome research in HIV infection

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Review

Host proteome research in HIV infection

Lijun Zhang et al. Genomics Proteomics Bioinformatics. 2010 Mar.

Abstract

Proteomics has been widely used in the last few years to look for new biomarkers and decipher the mechanism of HIV-host interaction. Herein, we review the recent developments of HIV/AIDS proteomic research, including the samples used in HIV/AIDS related research, the technologies used for proteomic study, the diagnosis biomarkers of HIV-associated disease especially HIV-associated neurocognitive impairment, the mechanisms of HIV-host interaction, HIV-associated dementia, substance abuse, and so on. In the end of this review, we also give some prospects about the limitation and future improvement of HIV/AIDS proteomic research.

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Figure 1
Figure 1
Illustration of the host proteome research in HIV infection.

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References

    1. List E.O. The use of proteomics to study infectious diseases. Infect. Disord. Drug Targets. 2008;8:31–45. - PubMed
    1. Noorbakhsh F. Deciphering complex mechanisms in neurodegenerative diseases: the advent of systems biology. Trends Neurosci. 2009;32:88–100. - PubMed
    1. Wiederin J. Biomarkers of HIV-1 associated dementia: proteomic investigation of sera. Proteome Sci. 2009;7:8. - PMC - PubMed
    1. Kim S.S. Different isoforms of apolipoprotein AI present heterologous post-translational expression in HIV infected patients. J. Proteome Res. 2007;6:180–184. - PubMed
    1. Pendyala G. Cerebrospinal fluid proteomics reveals potential pathogenic changes in the brains of SIV-infected monkeys. J. Proteome Res. 2009;8:2253–2260. - PMC - PubMed

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