Host proteome research in HIV infection
- PMID: 20451157
- PMCID: PMC5054115
- DOI: 10.1016/S1672-0229(10)60001-0
Host proteome research in HIV infection
Abstract
Proteomics has been widely used in the last few years to look for new biomarkers and decipher the mechanism of HIV-host interaction. Herein, we review the recent developments of HIV/AIDS proteomic research, including the samples used in HIV/AIDS related research, the technologies used for proteomic study, the diagnosis biomarkers of HIV-associated disease especially HIV-associated neurocognitive impairment, the mechanisms of HIV-host interaction, HIV-associated dementia, substance abuse, and so on. In the end of this review, we also give some prospects about the limitation and future improvement of HIV/AIDS proteomic research.
2010 Beijing Genomics Institute. Published by Elsevier Ltd. All rights reserved.
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