Merozoite surface proteins of the malaria parasite: the MSP1 complex and the MSP7 family
- PMID: 20451527
- DOI: 10.1016/j.ijpara.2010.04.008
Merozoite surface proteins of the malaria parasite: the MSP1 complex and the MSP7 family
Abstract
The first interaction between the malaria merozoite and the red blood cell it will invade is mediated by molecules on the surface of the two cells. The Plasmodium falciparum merozoite surface protein (MSP)1 complex that contains MSP1 and two other parasite proteins, MSP6 and MSP7, is likely to be an important component in this process. This article reviews the role of the MSP1 complex in the biology of the host parasite interface with a focus on MSP7 and related proteins that are coded by gene families in each of the different Plasmodium spp.
Copyright 2010 Australian Society for Parasitology Inc. Published by Elsevier Ltd. All rights reserved.
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