Insightful tales from single embryonic cells
- PMID: 20452308
- DOI: 10.1016/j.stem.2010.04.008
Insightful tales from single embryonic cells
Abstract
Two studies by Guo et al. (2010) and Tang et al. (2010) use comprehensive and systematic single-cell RNA profiling to address pivotal questions in mouse embryonic biology: when initial asymmetries become apparent during development and how cells adapt to an in vitro environment to become embryonic stem cells.
Comment on
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Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.Dev Cell. 2010 Apr 20;18(4):675-85. doi: 10.1016/j.devcel.2010.02.012. Dev Cell. 2010. PMID: 20412781
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Tracing the derivation of embryonic stem cells from the inner cell mass by single-cell RNA-Seq analysis.Cell Stem Cell. 2010 May 7;6(5):468-78. doi: 10.1016/j.stem.2010.03.015. Cell Stem Cell. 2010. PMID: 20452321 Free PMC article.
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