Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2010 Feb 26;15(2):79-80.
doi: 10.1186/2047-783x-15-2-79.

Kaposi sarcoma in a HIV uninfected man who has sex with men

Affiliations
Case Reports

Kaposi sarcoma in a HIV uninfected man who has sex with men

Anja Potthoff et al. Eur J Med Res. .

Abstract

Kaposi's sarcoma (KS) is a rare angioproliferative tumor associated with human herpesvirus 8 (HHV-8) infection. Four clinical variants of KS have been described: classic, endemic, iatrogenic and HIV-associated. We describe a 53-year-old men who had sex with men with a rapidly growing nodule on his left foot. Histologically KS was confirmed. Our patient did not match the clinical subgroups as HIV infection or other immune disorders could be ruled out. KS in HIV-negative MSM has only been reported sporadically. It was shown that KS in these patients clinically resembles classic KS but occurs at a younger age, is limited to the skin, and is associated with a good prognosis.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Clinical presentation of the patient's Kaposi sarcoma. A rapidly growing bluish nodule is located on the patient's left foot.
Figure 2
Figure 2
Immunohistochemical analysis for human herpesvirus 8 (HHV-8) in Kaposi sarcoma. Strong immunoreactivity of HHV-8 is present in the patient's skin lesion (hematoxylin, original magnification × 200).

Similar articles

Cited by

References

    1. Friedman-Kien AE, Saltzman BR, Cao YZ. et al.Kaposi's sarcoma in HIV-negative homosexual men. Lancet. 1990;335(8682):168–169. - PubMed
    1. García-Muret MP, Pujol RM, Puig L, Moreno A, de Moragas JM. Disseminated Kaposi's sarcoma not associated with HIV infection in a bisexual man. J Am Acad Dermatol. 1990;23:1035–1038. doi: 10.1016/0190-9622(90)70332-C. - DOI - PubMed
    1. Lanternier F, Lebbé C, Schartz N. et al.Kaposi's sarcoma in HIV-negative men having sex with men. AIDS. 2008;22(10):1163–1168. doi: 10.1097/QAD.0b013e3283031a8a. - DOI - PubMed
    1. Pauk J, Huang ML, Brodie SJ. et al.Mucosal shedding of human herpesvirus 8 in men. N Engl J Med. 2000;343(19):1369–1377. doi: 10.1056/NEJM200011093431904. - DOI - PubMed
    1. Maurer T, Ponte M, Leslie K. et al.Kaposi's sarcoma in HIV-negative men having sex with men. N Engl J Med. 2007;357(13):1352–1353. doi: 10.1056/NEJMc070508. - DOI - PubMed

Publication types