Animal models of neurological disease
- PMID: 20455493
- DOI: 10.1007/978-1-4419-5819-8_3
Animal models of neurological disease
Abstract
The use of animal models to study human pathology has proved valuable in a number of fields. Animal models of neurological disease have successfully and accurately recreated many aspects of human illness allowing for in-depth study ofneuropathophysiology. These models have been the source of a plethora of information, such as the importance of certain molecular mechanisms and genetic contributions in neurological disease. Additionally, animal models have been utilized in the discovery and testing of possible therapeutic treatments. Although most neurological diseases are still not yet completely understood and reliable treatment is lacking, animal models provide a major step in the right direction.
Similar articles
-
Methamphetamine fails to alter the noradrenergic integrity of the heart.Ann N Y Acad Sci. 2008 Oct;1139:337-44. doi: 10.1196/annals.1432.017. Ann N Y Acad Sci. 2008. PMID: 18991879
-
Experimental models of Parkinson's disease: insights from many models.Lab Anim Sci. 1999 Aug;49(4):363-71. Lab Anim Sci. 1999. PMID: 10480640 Review.
-
Progressive dopamine neuron loss in Parkinson's disease: the multiple hit hypothesis.Cell Transplant. 2006;15(3):239-50. doi: 10.3727/000000006783981990. Cell Transplant. 2006. PMID: 16719059 Review.
-
Sensitivity of zebrafish to environmental toxins implicated in Parkinson's disease.Neurotoxicol Teratol. 2004 Nov-Dec;26(6):857-64. doi: 10.1016/j.ntt.2004.06.014. Neurotoxicol Teratol. 2004. PMID: 15451049
-
Extranigral neurodegeneration in Parkinson's disease.Ann N Y Acad Sci. 2008 Oct;1139:331-6. doi: 10.1196/annals.1432.002. Ann N Y Acad Sci. 2008. PMID: 18991878
Cited by
-
Methodological Aspects for Preclinical Evaluation of Gadolinium Presence in Brain Tissue: Critical Appraisal and Suggestions for Harmonization-A Joint Initiative.Invest Radiol. 2018 Sep;53(9):499-517. doi: 10.1097/RLI.0000000000000467. Invest Radiol. 2018. PMID: 29659381 Free PMC article. Review.
-
ND-AMD: A Web-Based Database for Animal Models of Neurological Disease With Analysis Tools.CNS Neurosci Ther. 2025 May;31(5):e70411. doi: 10.1111/cns.70411. CNS Neurosci Ther. 2025. PMID: 40344361 Free PMC article.
-
Gadolinium Retention, Brain T1 Hyperintensity, and Endogenous Metals: A Comparative Study of Macrocyclic Versus Linear Gadolinium Chelates in Renally Sensitized Rats.Invest Radiol. 2018 Jun;53(6):328-337. doi: 10.1097/RLI.0000000000000447. Invest Radiol. 2018. PMID: 29329151 Free PMC article.
-
Stem cells: a model for screening, discovery and development of drugs.Stem Cells Cloning. 2011 Sep 27;4:51-9. doi: 10.2147/SCCAA.S16417. eCollection 2011. Stem Cells Cloning. 2011. PMID: 24198530 Free PMC article. Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical