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. 2010 May;26(5):527-32.
doi: 10.1089/aid.2009.0237.

The hepatitis C virus 5'UTR genomic region remains highly conserved under HAART: a 4- to 8-year longitudinal study from HCV/HIV co-infected patients

Franco Moretti  1 , Federico Bolcic, Lilia Mammana, Maria Belen Bouzas, Natalia Laufer, Jorge Quarleri
Affiliations

The hepatitis C virus 5'UTR genomic region remains highly conserved under HAART: a 4- to 8-year longitudinal study from HCV/HIV co-infected patients

Franco Moretti et al. AIDS Res Hum Retroviruses. 2010 May.
No abstract available

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Figures

FIG. 1.
FIG. 1.
Patient-by-patient dynamics of viral, immune, and biochemical parameters during the follow-up are plotted as a function of time (expressed in years in the x-axis). Individual alignment of partial (nucleotide 106 to 244) 5′UTR consensus nucleotide sequences from yearly sequential HCV strains characterized from consecutive plasma samples and PBMCs samples. HCV isolates belonging to genotype 1 are those from patients I, IV, VI, VII, VIII, IX, and X; genotype 2 are those from patient II, and genotype 3 are those from patients III and V. , Hepatitis C virus-RNA: (log10 scale IU/ml); , HIV (log10 scale copies/ml); gray curve, CD4 T cell count (cells/ml); and , ALT (IU × 10/ml).
FIG. 1.
FIG. 1.
Patient-by-patient dynamics of viral, immune, and biochemical parameters during the follow-up are plotted as a function of time (expressed in years in the x-axis). Individual alignment of partial (nucleotide 106 to 244) 5′UTR consensus nucleotide sequences from yearly sequential HCV strains characterized from consecutive plasma samples and PBMCs samples. HCV isolates belonging to genotype 1 are those from patients I, IV, VI, VII, VIII, IX, and X; genotype 2 are those from patient II, and genotype 3 are those from patients III and V. , Hepatitis C virus-RNA: (log10 scale IU/ml); , HIV (log10 scale copies/ml); gray curve, CD4 T cell count (cells/ml); and , ALT (IU × 10/ml).
FIG. 1.
FIG. 1.
Patient-by-patient dynamics of viral, immune, and biochemical parameters during the follow-up are plotted as a function of time (expressed in years in the x-axis). Individual alignment of partial (nucleotide 106 to 244) 5′UTR consensus nucleotide sequences from yearly sequential HCV strains characterized from consecutive plasma samples and PBMCs samples. HCV isolates belonging to genotype 1 are those from patients I, IV, VI, VII, VIII, IX, and X; genotype 2 are those from patient II, and genotype 3 are those from patients III and V. , Hepatitis C virus-RNA: (log10 scale IU/ml); , HIV (log10 scale copies/ml); gray curve, CD4 T cell count (cells/ml); and , ALT (IU × 10/ml).
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References

    1. Roe B. Hall WW. Cellular and molecular interactions in coinfection with hepatitis C virus and human immunodeficiency virus. Expert Rev Mol Med. 2008;10:30. - PubMed
    1. Laskus T. Radkowski M. Piasek A, et al. Hepatitis C virus in lymphoid cells of patients coinfected with human immunodeficiency virus type 1: evidence of active replication in monocytes/macrophages and lymphocytes. J Infect Dis. 2000;181(2):442–448. - PubMed
    1. Barría MI. González A. Vera-Otarola J, et al. Analysis of natural variants of the hepatitis C virus internal ribosome entry site reveals that primary sequence plays a key role in cap-independent translation. Nucleic Acids Res. 2009;37(3):957–971. - PMC - PubMed
    1. López-Labrador FX. Dove L. Hui CK, et al. Trends for genetic variation of hepatitis C virus quasispecies in human immunodeficiency virus-1 coinfected patients. Virus Res. 2007;130:285–291. - PMC - PubMed
    1. Shuhart MC. Sullivan DG. Bekele K, et al. HIV infection and antiretroviral therapy: effect on hepatitis C virus quasispecies variability. J Infect Dis. 2006;193(9):1211–1218. - PubMed

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