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Review

. 2010 May 18;107(20):9027-8.

doi: 10.1073/pnas.1005440107. Epub 2010 May 10.

Conservation and divergence in eukaryotic DNA methylation

Tzuu-Fen Lee¹, Jixian Zhai, Blake C Meyers

Affiliations

PMID: 20457928
PMCID: PMC2889049
DOI: 10.1073/pnas.1005440107

Review

Conservation and divergence in eukaryotic DNA methylation

Tzuu-Fen Lee et al. Proc Natl Acad Sci U S A. 2010.

. 2010 May 18;107(20):9027-8.

doi: 10.1073/pnas.1005440107. Epub 2010 May 10.

Authors

Tzuu-Fen Lee¹, Jixian Zhai, Blake C Meyers

Affiliation

¹ Department of Plant and Soil Sciences and Delaware Biotechnology Institute, University of Delaware, Newark, DE 19711, USA.

PMID: 20457928
PMCID: PMC2889049
DOI: 10.1073/pnas.1005440107

No abstract available

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest.

Figures

Fig. 1. — Fig. 1.
Conserved DNA methylation patterns in eukaryotes. Although different methylation contexts are found in animals (CG) and plants (CG, CHG, CHH), gene-body methylation is conserved among eukaryotes. Transposable elements (TEs) are methylated in flowering plants in CG, CHG, and CHH contexts, as well as in a CG context in the green algae and sea squirt genomes. In green algae, non-CG methylation is more enriched in exons of genes compared with TEs and repeats (7). Fungi, not shown in the figure, have genomes generally unmethylated in active genes but heavily methylated at TEs and repeats (6).

See this image and copyright information in PMC

Comment on

Conservation and divergence of methylation patterning in plants and animals.
Feng S, Cokus SJ, Zhang X, Chen PY, Bostick M, Goll MG, Hetzel J, Jain J, Strauss SH, Halpern ME, Ukomadu C, Sadler KC, Pradhan S, Pellegrini M, Jacobsen SE. Feng S, et al. Proc Natl Acad Sci U S A. 2010 May 11;107(19):8689-94. doi: 10.1073/pnas.1002720107. Epub 2010 Apr 15. Proc Natl Acad Sci U S A. 2010. PMID: 20395551 Free PMC article.

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