Comment on

• Urinary clusterin, cystatin C, beta2-microglobulin and total protein as markers to detect drug-induced kidney injury.

  Dieterle F, Perentes E, Cordier A, Roth DR, Verdes P, Grenet O, Pantano S, Moulin P, Wahl D, Mahl A, End P, Staedtler F, Legay F, Carl K, Laurie D, Chibout SD, Vonderscher J, Maurer G. Dieterle F, et al. Nat Biotechnol. 2010 May;28(5):463-9. doi: 10.1038/nbt.1622. Nat Biotechnol. 2010. PMID: 20458316
• Urinary biomarkers trefoil factor 3 and albumin enable early detection of kidney tubular injury.

  Yu Y, Jin H, Holder D, Ozer JS, Villarreal S, Shughrue P, Shi S, Figueroa DJ, Clouse H, Su M, Muniappa N, Troth SP, Bailey W, Seng J, Aslamkhan AG, Thudium D, Sistare FD, Gerhold DL. Yu Y, et al. Nat Biotechnol. 2010 May;28(5):470-7. doi: 10.1038/nbt.1624. Nat Biotechnol. 2010. PMID: 20458317
• Kidney injury molecule-1 outperforms traditional biomarkers of kidney injury in preclinical biomarker qualification studies.

  Vaidya VS, Ozer JS, Dieterle F, Collings FB, Ramirez V, Troth S, Muniappa N, Thudium D, Gerhold D, Holder DJ, Bobadilla NA, Marrer E, Perentes E, Cordier A, Vonderscher J, Maurer G, Goering PL, Sistare FD, Bonventre JV. Vaidya VS, et al. Nat Biotechnol. 2010 May;28(5):478-85. doi: 10.1038/nbt.1623. Nat Biotechnol. 2010. PMID: 20458318 Free PMC article.
• A panel of urinary biomarkers to monitor reversibility of renal injury and a serum marker with improved potential to assess renal function.

  Ozer JS, Dieterle F, Troth S, Perentes E, Cordier A, Verdes P, Staedtler F, Mahl A, Grenet O, Roth DR, Wahl D, Legay F, Holder D, Erdos Z, Vlasakova K, Jin H, Yu Y, Muniappa N, Forest T, Clouse HK, Reynolds S, Bailey WJ, Thudium DT, Topper MJ, Skopek TR, Sina JF, Glaab WE, Vonderscher J, Maurer G, Chibout SD, Sistare FD, Gerhold DL. Ozer JS, et al. Nat Biotechnol. 2010 May;28(5):486-94. doi: 10.1038/nbt.1627. Nat Biotechnol. 2010. PMID: 20458319