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Randomized Controlled Trial
. 2010 Sep;19(7):1025-33.
doi: 10.1007/s11136-010-9669-6. Epub 2010 May 11.

Changes in Health-Related Quality of Life among African-Americans in a lifestyle weight loss program

Aluko A Hope  1 , Shiriki K Kumanyika, Justine Shults, William C Holmes
Affiliations
Randomized Controlled Trial

Changes in Health-Related Quality of Life among African-Americans in a lifestyle weight loss program

Aluko A Hope et al. Qual Life Res. 2010 Sep.

Abstract

Purpose: Changes in health-related quality of life (HRQoL) were assessed in clinically obese, African-American adults after completion of a weight loss program that resulted in modest average weight loss.

Methods: Data were analyzed for 87 men and women who provided weight measurements after an initial 10-week weight loss program (Phase 1) and a subsequent clinical trial to evaluate three weight maintenance approaches (Phase 2) over an additional 8 to 18 months. HRQoL was assessed using the Short Form SF-36 questionnaire. Intra-person changes in HRQoL were assessed and analyzed for associations with weight change within each phase. Non-parametric bivariable analyses and multivariable linear regression were used in statistical analyses.

Results: Changes in HRQoL were modest; clinically significant intra-subject improvements in SF-36 domains of general health and vitality and in the mental component summary score were observed after Phase 1 but were attenuated during Phase 2. Improvements in vitality were significantly associated with greater weight loss in Phase 1, but no HRQoL change scores during Phase 2 were associated with weight change.

Conclusions: Short-term improvements in general health and vitality were observed. The vitality domain of the SF-36 appeared to be the domain of HRQoL most responsive to modest weight change.

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Conflict of interest statement

Conflict of interest statement The authors declare that they have no competing interests.

Figures

Fig. 1
Fig. 1
shows the percent of participants with decreased (change score < 0), stable (change score = 0) or improved SF-36 (change score > 0) scores after each phase of the study for the eight SF-36 domains. The eight SF-36 domains are: PF—physical functioning; RP—role limitations due physical health; BP—bodily pain; GH—general health; VT—vitality; SF—social functioning; RE –role limitations due to emotional health; MH—mental health. The number after each domain refers to the phase of the study: 1—Phase 1 (the intensive weight loss phase); 2—Phase 2 (the weight maintenance phase). Change scores for Phase 2 refer to changes in HRQoL that occurred after Phase 1, from enrollment in Phase 2 to the end of the study. See text for further details on how the change scores for each phase were calculated. In general, the RP, RE and SF domains appeared minimally responsive; most participants in either phase reported no change in these domain scores. The percentage of participants with improvements in HRQoL was higher in Phase 1 compared to Phase 2 while the percentage of participants with declines was higher in Phase 2 compared to Phase 1
See this image and copyright information in PMC

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