What types of inappropriate prescribing predict adverse drug reactions in older adults?
- PMID: 20460555
- PMCID: PMC4890145
- DOI: 10.1345/aph.1P182
What types of inappropriate prescribing predict adverse drug reactions in older adults?
Abstract
Adverse drug events happen all too often in older adults, but we still do not have a clear understanding of potentially modifiable risk factors, with the exception of polypharmacy. This paper critiques the article in this issue of The Annals entitled, "Inappropriate Prescribing Predicts Adverse Drug Events in Older Adults." A validated measure for self-reported adverse drug events was used, along with a modified measure for inappropriate prescribing that we developed nearly 2 decades ago (ie, Medication Appropriateness Index). Besides discussing the strengths and weaknesses of this article, we also recommend future research directions in this area.
Conflict of interest statement
Comment on
-
Inappropriate prescribing predicts adverse drug events in older adults.Ann Pharmacother. 2010 Jun;44(6):957-63. doi: 10.1345/aph.1m657. Epub 2010 May 11. Ann Pharmacother. 2010. PMID: 20460558 Clinical Trial.
References
-
- Chrischilles EA, Segar ET, Wallace RB. Self-reported adverse drug reactions and related resource use: a study of community-dwelling persons 65 years of age and older. Ann Intern Med. 1992;117:634–40. - PubMed
-
- Hanlon JT, Schmader KE, Koronkowski MJ, et al. Adverse drug events in high risk elderly outpatients. J Am Geriatr Soc. 1997;45:945–8. - PubMed
-
- Hanlon JT, Pieper CF, Hajjar ER, et al. Incidence and predictors of all and preventable adverse drug reactions in frail elderly post hospital stay. J Gerontol Med Sci. 2006;61A:511–5. Abstract/FREE Full Text. - PubMed
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources
Medical
