Hepatitis B and Renal Disease

doi:10.1007/s11901-010-0042-6

. 2010 May;9(2):99-105.

doi: 10.1007/s11901-010-0042-6. Epub 2010 Apr 14.

Hepatitis B and Renal Disease

Tak Mao Chan¹

Affiliations

PMID: 20461128
PMCID: PMC2861764
DOI: 10.1007/s11901-010-0042-6

Hepatitis B and Renal Disease

Tak Mao Chan. Curr Hepat Rep. 2010 May.

. 2010 May;9(2):99-105.

doi: 10.1007/s11901-010-0042-6. Epub 2010 Apr 14.

Author

Tak Mao Chan¹

Affiliation

¹ Department of Medicine, University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong, China.

PMID: 20461128
PMCID: PMC2861764
DOI: 10.1007/s11901-010-0042-6

Abstract

Glomerulonephritis is an important extrahepatic manifestation of chronic hepatitis B virus (HBV) infection. The uncommon occurrence, variability in renal histopathology, and heterogeneity in clinical course present challenges in clinical studies and have resulted in a relative paucity of data and uncertainty with regard to the optimal management of HBV-related glomerular diseases. The advent of nucleos(t)ide analogue medications that effectively suppress HBV replication has markedly altered the clinical outcomes of kidney transplant recipients with HBV infection, but the emergence of drug resistance is an escalating problem. This article reviews the recent knowledge of the pathogenesis and treatment of HBV-related membranous nephropathy, and discusses the management of hepatitis B in kidney transplant recipients, which is continuously evolving.

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References

1. Zeng CH, Chen HM, Wang RS, et al. Etiology and clinical characteristics of membranous nephropathy in Chinese patients. Am J Kidney Dis. 2008;52:691–698. doi: 10.1053/j.ajkd.2008.06.006. - DOI - PubMed
1. Levy M, Chen N: Worldwide perspective of hepatitis B-associated glomerulonephritis in the 80s. Kidney Int 1991, Suppl 35:S24–S33. - PubMed
1. Khaira A, Upadhyay BK, Sharma A, et al. Hepatitis B virus associated focal and segmental glomerular sclerosis: report of two cases and review of literature. Clin Exp Nephrol. 2009;13:373–377. doi: 10.1007/s10157-008-0124-8. - DOI - PubMed
1. Park MH, Song EY, Ahn C, et al. Two Subtypes of hepatitis B virus-associated glomerulonephritis are associated with different HLA-DR2 alleles in Koreans. Tissue Antigens. 2003;62:505–511. doi: 10.1046/j.1399-0039.2003.00141.x. - DOI - PubMed
1. Chen L, Wu C, Fan X, et al. Replication and infectivity of hepatitis B virus in HBV-related glomerulonephritis. Int J Infect Dis. 2009;13:394–398. doi: 10.1016/j.ijid.2008.08.014. - DOI - PubMed

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[1] Zeng CH, Chen HM, Wang RS, et al. Etiology and clinical characteristics of membranous nephropathy in Chinese patients. Am J Kidney Dis. 2008;52:691–698. doi: 10.1053/j.ajkd.2008.06.006. - DOI - PubMed

[2] Zeng CH, Chen HM, Wang RS, et al. Etiology and clinical characteristics of membranous nephropathy in Chinese patients. Am J Kidney Dis. 2008;52:691–698. doi: 10.1053/j.ajkd.2008.06.006. - DOI - PubMed

[3] Levy M, Chen N: Worldwide perspective of hepatitis B-associated glomerulonephritis in the 80s. Kidney Int 1991, Suppl 35:S24–S33. - PubMed

[4] Levy M, Chen N: Worldwide perspective of hepatitis B-associated glomerulonephritis in the 80s. Kidney Int 1991, Suppl 35:S24–S33. - PubMed

[5] Khaira A, Upadhyay BK, Sharma A, et al. Hepatitis B virus associated focal and segmental glomerular sclerosis: report of two cases and review of literature. Clin Exp Nephrol. 2009;13:373–377. doi: 10.1007/s10157-008-0124-8. - DOI - PubMed

[6] Khaira A, Upadhyay BK, Sharma A, et al. Hepatitis B virus associated focal and segmental glomerular sclerosis: report of two cases and review of literature. Clin Exp Nephrol. 2009;13:373–377. doi: 10.1007/s10157-008-0124-8. - DOI - PubMed

[7] Park MH, Song EY, Ahn C, et al. Two Subtypes of hepatitis B virus-associated glomerulonephritis are associated with different HLA-DR2 alleles in Koreans. Tissue Antigens. 2003;62:505–511. doi: 10.1046/j.1399-0039.2003.00141.x. - DOI - PubMed

[8] Park MH, Song EY, Ahn C, et al. Two Subtypes of hepatitis B virus-associated glomerulonephritis are associated with different HLA-DR2 alleles in Koreans. Tissue Antigens. 2003;62:505–511. doi: 10.1046/j.1399-0039.2003.00141.x. - DOI - PubMed

[9] Chen L, Wu C, Fan X, et al. Replication and infectivity of hepatitis B virus in HBV-related glomerulonephritis. Int J Infect Dis. 2009;13:394–398. doi: 10.1016/j.ijid.2008.08.014. - DOI - PubMed

[10] Chen L, Wu C, Fan X, et al. Replication and infectivity of hepatitis B virus in HBV-related glomerulonephritis. Int J Infect Dis. 2009;13:394–398. doi: 10.1016/j.ijid.2008.08.014. - DOI - PubMed

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Hepatitis B and Renal Disease

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Hepatitis B and Renal Disease

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