Comment
doi: 10.1016/j.str.2010.04.003.
Class II cytokine common receptors: something old, something new
Affiliations
- PMID: 20462488
- DOI: 10.1016/j.str.2010.04.003
Item in Clipboard
Comment
Class II cytokine common receptors: something old, something new
Structure.
.
Free article
Abstract
In this issue of Structure, Yoon and colleagues provide models of a low affinity cytokine common receptor, IL-10R2, in a ternary complex with two class II cytokines and their corresponding ligand-specific receptors, revealing the nature of their promiscuous interactions.
Comment on
-
Structure and mechanism of receptor sharing by the IL-10R2 common chain.Structure. 2010 May 12;18(5):638-48. doi: 10.1016/j.str.2010.02.009. Structure. 2010. PMID: 20462497 Free PMC article.
Similar articles
-
Temporal associations between interleukin 22 and the extracellular domains of IL-22R and IL-10R2.Int Immunopharmacol. 2004 May;4(5):693-708. doi: 10.1016/j.intimp.2004.01.010. Int Immunopharmacol. 2004. PMID: 15120653 Review.
-
Is there an interaction between interleukin-10 and interleukin-22?Genes Immun. 2005 Feb;6(1):8-18. doi: 10.1038/sj.gene.6364144. Genes Immun. 2005. PMID: 15526001
-
Activation of the signal transducer glycoprotein 130 by both IL-6 and IL-11 requires two distinct binding epitopes.J Immunol. 1999 Feb 1;162(3):1480-7. J Immunol. 1999. PMID: 9973404
-
Class II cytokine receptors and their ligands: key antiviral and inflammatory modulators.Nat Rev Immunol. 2003 Aug;3(8):667-76. doi: 10.1038/nri1153. Nat Rev Immunol. 2003. PMID: 12974481 Review.
-
The IL-10R2 binding hot spot on IL-22 is located on the N-terminal helix and is dependent on N-linked glycosylation.J Mol Biol. 2004 Sep 10;342(2):503-14. doi: 10.1016/j.jmb.2004.07.069. J Mol Biol. 2004. PMID: 15327950
Publication types
LinkOut - more resources
Full Text Sources
