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Review
. 2010 Jul;27(7):996-1047.
doi: 10.1039/b816430b. Epub 2010 May 12.

Biosynthesis of polyketides by trans-AT polyketide synthases

Jörn Piel  1
Affiliations
Review

Biosynthesis of polyketides by trans-AT polyketide synthases

Jörn Piel. Nat Prod Rep. 2010 Jul.

Abstract

This review discusses the biosynthesis of natural products that are generated by trans-AT polyketide synthases, a family of catalytically versatile enzymes that have recently been recognized as one of the major group of proteins involved in the production of bioactive polyketides. 436 references are cited.

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