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Case Reports
. 2010 Jun;62(6):1050-2.
doi: 10.1016/j.jaad.2009.01.029.

Rosaceiform dermatitis associated with topical tacrolimus treatment

Shoko Fujiwara  1 , Yukari Okubo, Ryokichi Irisawa, Ryoji Tsuboi
Affiliations
Case Reports

Rosaceiform dermatitis associated with topical tacrolimus treatment

Shoko Fujiwara et al. J Am Acad Dermatol. 2010 Jun.

Abstract

We describe herein 3 patients who developed rosacea-like dermatitis eruptions while using 0.03% or 0.1% tacrolimus ointment for facial dermatitis. Skin biopsy specimens showed telangiectasia and noncaseating epithelioid granulomatous tissue formation in the papillary to mid dermis. Continuous topical use of immunomodulators such as tacrolimus or pimecrolimus should be regarded as a potential cause of rosaceiform dermatitis, although many cases have not been reported.

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