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Comment
. 2010 May 14;328(5980):825; author reply 825.
doi: 10.1126/science.1183545.

Comment on "Detection of an infectious retrovirus, XMRV, in blood cells of patients with chronic fatigue syndrome"

Cathie Sudlow  1 , Malcolm Macleod, Rustam Al-Shahi Salman, Jon Stone
Affiliations
Comment

Comment on "Detection of an infectious retrovirus, XMRV, in blood cells of patients with chronic fatigue syndrome"

Cathie Sudlow et al. Science. .

Abstract

Lombardi et al. (Reports, 23 October 2009, p. 585) reported an association between the human gammaretrovirus XMRV and chronic fatigue syndrome. However, their results may be misleading because of various potential sources of bias and confounding. If real, the association may lack generalizability because of the specific characteristics of the cases studied and could be due to reverse causality.

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