Cardiovascular regulation after stroke: evidence of impairment, trainability, and implications for rehabilitation
- PMID: 20467516
- PMCID: PMC2845242
Cardiovascular regulation after stroke: evidence of impairment, trainability, and implications for rehabilitation
Abstract
Purpose: To discuss the role of the vascular system and regulation of blood flow delivery in individuals with chronic stroke. This paper will discuss mechanisms of blood flow, vascular remodeling in chronic stroke, exercise as an intervention to improve blood flow delivery, and the role of physical therapy practice in promoting exercise.
Key points: Evidence suggests that people with chronic stroke may experience reduced blood flow and decreased arterial diameter in the hemiparetic limb. These arterial changes may influence exercise performance and functional ambulation. However, exercise training can be an effective intervention for improving blood flow delivery in the hemiparetic limb. Statement of Recommendations: Physical therapists working with people post-stroke should routinely prescribe aerobic exercise training within the plan of care during stroke rehabilitation. This may minimize declines in the cardiorespiratory and vascular systems and provide greater functional capacity to perform functional activities during and after discharge from physical therapy services.
Keywords: blood flow; cardiovascular; exercise; stroke.
Similar articles
-
Task-oriented aerobic exercise in chronic hemiparetic stroke: training protocols and treatment effects.Top Stroke Rehabil. 2005 Winter;12(1):45-57. doi: 10.1310/PJQN-KAN9-TTVY-HYQH. Top Stroke Rehabil. 2005. PMID: 15736000 Review.
-
Treadmill aerobic exercise training reduces the energy expenditure and cardiovascular demands of hemiparetic gait in chronic stroke patients. A preliminary report.Stroke. 1997 Feb;28(2):326-30. doi: 10.1161/01.str.28.2.326. Stroke. 1997. PMID: 9040684
-
Single limb exercise: pilot study of physiological and functional responses to forced use of the hemiparetic lower extremity.Top Stroke Rehabil. 2010 Mar-Apr;17(2):128-39. doi: 10.1310/tsr1702-128. Top Stroke Rehabil. 2010. PMID: 20542855 Free PMC article.
-
Treadmill exercise rehabilitation improves ambulatory function and cardiovascular fitness in patients with chronic stroke: a randomized, controlled trial.Stroke. 2005 Oct;36(10):2206-11. doi: 10.1161/01.STR.0000181076.91805.89. Epub 2005 Sep 8. Stroke. 2005. PMID: 16151035 Clinical Trial.
-
Aerobic exercise prior to task-specific training to improve poststroke motor function: A case series.Physiother Res Int. 2018 Apr;23(2):e1707. doi: 10.1002/pri.1707. Epub 2018 Feb 13. Physiother Res Int. 2018. PMID: 29436126 Review.
Cited by
-
Why Should Physical Therapists Care about Their Patients' Diet?Physiother Can. 2017;69(2):99-103. doi: 10.3138/ptc.69.2.GEE. Physiother Can. 2017. PMID: 28539689 Free PMC article. No abstract available.
-
Variables influencing wearable sensor outcome estimates in individuals with stroke and incomplete spinal cord injury: a pilot investigation validating two research grade sensors.J Neuroeng Rehabil. 2018 Mar 13;15(1):19. doi: 10.1186/s12984-018-0358-y. J Neuroeng Rehabil. 2018. PMID: 29534737 Free PMC article.
-
Motor Impairment and Disuse Are Independent Predictors of Vascular Outcomes Poststroke.Phys Ther. 2025 Mar 3;105(3):pzaf002. doi: 10.1093/ptj/pzaf002. Phys Ther. 2025. PMID: 39982425 Free PMC article.
-
Movement-Based Priming: Clinical Applications and Neural Mechanisms.J Mot Behav. 2017 Jan-Feb;49(1):88-97. doi: 10.1080/00222895.2016.1250716. Epub 2017 Mar 1. J Mot Behav. 2017. PMID: 28277966 Free PMC article. Review.
-
Peripheral vascular function in stroke: systematic review and meta-analysis.J Appl Physiol (1985). 2024 May 1;136(5):1182-1194. doi: 10.1152/japplphysiol.00601.2023. Epub 2024 Mar 14. J Appl Physiol (1985). 2024. PMID: 38482571 Free PMC article.
References
-
- Macko RF, DeSouza CA, Tretter LD, et al. Treadmill aerobic exercise training reduces the energy expenditure and cardiovascular demands of hemiparetic gait in chronic stroke patients. A preliminary report. Stroke. 1997;28(2):326–330. - PubMed
-
- Mohrman DE, Heller LJ. Cardiovascular Physiology. 6th ed. New York, NY: Lange Medical Books/McGraw-Hill; 2006.
-
- Kamiya A, Ando J, Shibata M, Masuda H. Roles of fluid shear stress in physiological regulation of vascular structure and function. Biorheology. 1988;25(1-2):271–278. - PubMed
-
- Parker BA, Smithmyer SL, Pelberg JA, Mishkin AD, Herr MD, Proctor DN. Sex differences in leg vasodilation during graded knee extensor exercise in young adults. J Appl Physiol. 2007;103(5):1583–1591. - PubMed
-
- Ivey FM, Gardner AW, Dobrovolny CL, Macko RF. Unilateral impairment of leg blood flow in chronic stroke patients. Cerebrovasc Dis. 2004;18(4):283–289. - PubMed
LinkOut - more resources
Full Text Sources