Adverse vaccinal events in dogs and cats

Abstract

Adverse vaccinal events, or perceived vaccine-associated adverse events, are relatively uncommon in companion animal practice. These events, however, often evoke great concern to owners and veterinarians. Because of the low incidence of these events and the large number of potential antigenic causes, exact mechanisms are often difficult to elucidate. This article reviews current evidence related to the immunologic basis of adverse events seen after canine and feline vaccination.