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Comment
. 2010 May 14;38(3):321-2.
doi: 10.1016/j.molcel.2010.04.018.

Chromatin compaction at Hox loci: a polycomb tale beyond histone tails

Jeffrey A Simon  1
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Chromatin compaction at Hox loci: a polycomb tale beyond histone tails

Jeffrey A Simon. Mol Cell. .
Free article

Abstract

A new study in this issue of Molecular Cell (Eskeland et al., 2010) implicates Polycomb repressive complex 1 (PRC1) in compacting Hox gene chromatin in mouse embryonic stem cells and suggests that compaction, rather than histone tail ubiquitylation, confers Hox gene silencing.

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