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Comment
. 2006 Nov;2(6):845-8.
doi: 10.1586/1744666X.2.6.845.

Novel therapeutic approach to counter the recruitment of circulating endothelial progenitor cells to tumors

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Comment

Novel therapeutic approach to counter the recruitment of circulating endothelial progenitor cells to tumors

Luis R Espinoza. Expert Rev Clin Immunol. 2006 Nov.

Abstract

Evaluation of: Shaked Y, Ciarrocchi A, Franco M et al. Therapy-induced acute recruitment of circulating endothelial progenitor cells to tumors. Science 313, 1785-1787 (2006). Recently gathered evidence indicates that bone marrow-derived circulating endothelial progenitor cells can contribute to tumor angiogenesis and the growth of certain tumors. The paper under evaluation presents a novel therapeutic approach that disrupts the recruitment of these cells by tumors, therefore facilitating the antitumor activity of chemotherapeutic agents.

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