Novel therapeutic approach to counter the recruitment of circulating endothelial progenitor cells to tumors
- PMID: 20476971
- DOI: 10.1586/1744666X.2.6.845
Novel therapeutic approach to counter the recruitment of circulating endothelial progenitor cells to tumors
Abstract
Evaluation of: Shaked Y, Ciarrocchi A, Franco M et al. Therapy-induced acute recruitment of circulating endothelial progenitor cells to tumors. Science 313, 1785-1787 (2006). Recently gathered evidence indicates that bone marrow-derived circulating endothelial progenitor cells can contribute to tumor angiogenesis and the growth of certain tumors. The paper under evaluation presents a novel therapeutic approach that disrupts the recruitment of these cells by tumors, therefore facilitating the antitumor activity of chemotherapeutic agents.
Comment on
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Therapy-induced acute recruitment of circulating endothelial progenitor cells to tumors.Science. 2006 Sep 22;313(5794):1785-7. doi: 10.1126/science.1127592. Science. 2006. PMID: 16990548
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