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Comment
. 2010 May 18;17(5):419-20.
doi: 10.1016/j.ccr.2010.04.020.

To infinium, and beyond!

Karen D Wright  1 , Richard J Gilbertson
Affiliations
Comment

To infinium, and beyond!

Karen D Wright et al. Cancer Cell. .

Abstract

Glioblastoma (GBM) is a malignant brain tumor that kills most patients within 2 years. In this issue of Cancer Cell, Noushmehr et al., through The Cancer Genome Atlas (TCGA) project, provide one of the first integrated views of the GBM methylome, adding to our increasingly comprehensive understanding of this disease.

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  • Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma.
    Noushmehr H, Weisenberger DJ, Diefes K, Phillips HS, Pujara K, Berman BP, Pan F, Pelloski CE, Sulman EP, Bhat KP, Verhaak RG, Hoadley KA, Hayes DN, Perou CM, Schmidt HK, Ding L, Wilson RK, Van Den Berg D, Shen H, Bengtsson H, Neuvial P, Cope LM, Buckley J, Herman JG, Baylin SB, Laird PW, Aldape K; Cancer Genome Atlas Research Network. Noushmehr H, et al. Cancer Cell. 2010 May 18;17(5):510-22. doi: 10.1016/j.ccr.2010.03.017. Epub 2010 Apr 15. Cancer Cell. 2010. PMID: 20399149 Free PMC article.

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