doi: 10.1093/jnci/60.4.875.
Effect of the Fv-1 locus in vivo: host range pseudotypes of murine sarcoma virus
- PMID: 204797
- DOI: 10.1093/jnci/60.4.875
Item in Clipboard
Effect of the Fv-1 locus in vivo: host range pseudotypes of murine sarcoma virus
J Natl Cancer Inst.
1978 Apr.
Abstract
Fv-1-specific host-range pseudotypes of murine sarcoma virus (MuSV) were developed by rescue from nonproducer cells with N- or B-tropic leukemia viruses. The MuSV(B) and MuSV(N) pseudotype viruses were tested in vitro and were restricted specifically by the Fv-1 gene locus. When the pseudo-type viruses were tested in vivo in mice of specific Fv-1 geno-types, tumor induction was completely restricted in nonpermissive animals, including athymic nude mice, whereas tumors grew progressively in permissive animals. All tumors regressed in adult heterozygous mice, but not in adult athymic nude mice.
Similar articles
-
Murine sarcoma virus pseudotypes used as immunogens against viral and chemical oncogenesis.Cancer Res. 1977 Jun;37(6):1768-76. Cancer Res. 1977. PMID: 192461
-
Effect of pseudotype on Abelson virus and Kirsten sarcoma virus-induced leukemia.J Exp Med. 1978 Apr 1;147(4):1044-53. doi: 10.1084/jem.147.4.1044. J Exp Med. 1978. PMID: 206644 Free PMC article.
-
Inherited resistance to N- and B-tropic murine leukemia viruses in vitro. Effect of the Fv-1 locus on the rescue of a replication-defective and transformation-defective murine sarcoma virus in the Fv-1 congenic strains SIM.S and SIM.R.Virology. 1977 Jun 15;79(2):302-11. doi: 10.1016/0042-6822(77)90357-9. Virology. 1977. PMID: 194408 No abstract available.
-
In vivo interactions between murine leukemia and sarcoma viruses.Bibl Haematol. 1975;(40):613-20. doi: 10.1159/000397582. Bibl Haematol. 1975. PMID: 169829
-
Moloney sarcoma virus-induced tumors in athymic (nude) mice: growth pattern and antibody responses.J Natl Cancer Inst. 1975 Mar;54(3):793-4. doi: 10.1093/jnci/54.3.793. J Natl Cancer Inst. 1975. PMID: 164570
Cited by
-
Reversal of Fv-1 host range by in vitro restriction endonuclease fragment exchange between molecular clones of N-tropic and B-tropic murine leukemia virus genomes.J Virol. 1983 Oct;48(1):110-9. doi: 10.1128/JVI.48.1.110-119.1983. J Virol. 1983. PMID: 6310140 Free PMC article.
-
Analysis of proteins of mouse sarcoma pseudotype viruses: type-specific radioimmunoassay for ecotropic virus p30's.J Virol. 1979 Jun;30(3):729-34. doi: 10.1128/JVI.30.3.729-734.1979. J Virol. 1979. PMID: 90164 Free PMC article.
-
Transfer of Fv-1 locus-specific resistance to murine N-tropic and B-tropic retroviruses by cytoplasmic RNA.J Virol. 1978 Aug;27(2):288-99. doi: 10.1128/JVI.27.2.288-299.1978. J Virol. 1978. PMID: 211261 Free PMC article.
-
Physical mapping of the Fv-1 tropism host range determinant of BALB/c murine leukemia viruses.J Virol. 1983 Dec;48(3):685-96. doi: 10.1128/JVI.48.3.685-696.1983. J Virol. 1983. PMID: 6313967 Free PMC article.
-
Effect of Fv-1 gene product on synthesis of linear and supercoiled viral DNA in cells infected with murine leukemia virus.J Virol. 1980 Jan;33(1):183-95. doi: 10.1128/JVI.33.1.183-195.1980. J Virol. 1980. PMID: 6245227 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
