Neurotoxic kinins from wasp and ant venoms
- PMID: 2048133
- DOI: 10.1016/0041-0101(91)90098-c
Neurotoxic kinins from wasp and ant venoms
Abstract
Kinins are polypeptides of 9-18 amino-acid residues containing a bradykinin-like sequence, in some cases as part of a molecule. The bradykinin-like sequence is either bradykinin, Hyp3-bradykinin or Thr6-bradykinin. Kinins are neurotoxic components of wasp and ant venoms, causing in the insect CNS a presynaptic block of the cholinergic transmission by means of an irreversible depletion, probably caused by a non-competitive inhibition of choline uptake.
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