Review
doi: 10.4049/jimmunol.0902567.
Small RNAs guide hematopoietic cell differentiation and function
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- PMID: 20483778
- DOI: 10.4049/jimmunol.0902567
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Review
Small RNAs guide hematopoietic cell differentiation and function
J Immunol.
.
Abstract
MicroRNAs (miRNAs) are key regulators of gene expression that help direct normal differentiation and malignant transformation of hematopoietic cells. This review summarizes our current knowledge of how miRNAs function in normal and malignant hematopoiesis and how miRNAs might be applied for disease treatment.
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