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. 2010 Aug;33(8):1771-7.
doi: 10.2337/dc10-0296. Epub 2010 May 18.

Risk of diabetes in U.S. military service members in relation to combat deployment and mental health

Edward J Boyko  1 , Isabel G Jacobson, Besa Smith, Margaret A K Ryan, Tomoko I Hooper, Paul J Amoroso, Gary D Gackstetter, Elizabeth Barrett-Connor, Tyler C Smith; Millennium Cohort Study Team
Collaborators, Affiliations

Risk of diabetes in U.S. military service members in relation to combat deployment and mental health

Edward J Boyko et al. Diabetes Care. 2010 Aug.

Abstract

Objective: Few prospective data exist on the risk of diabetes in individuals serving in the U.S. military. The objectives of this study were to determine whether military deployment, combat exposures, and mental health conditions were related to the risk of newly reported diabetes over 3 years.

Research design and methods: Data were from Millennium Cohort Study participants who completed baseline (July 2001-June 2003) and follow-up (June 2004-February 2006) questionnaires (follow-up response rate = 71.4%). After exclusion criteria were applied, adjusted analyses included 44,754 participants (median age 36 years, range 18-68 years). Survey instruments collected demographics, height, weight, lifestyle, military service, clinician-diagnosed diabetes, and other physical and mental health conditions. Deployment was defined by U.S. Department of Defense databases, and combat exposure was assessed by self-report at follow-up. Odds of newly reported diabetes were estimated using logistic regression analysis.

Results: Occurrence of diabetes during follow-up was 3 per 1,000 person-years. Individuals reporting diabetes at follow-up were significantly older, had greater baseline BMI, and were less likely to be Caucasian. After adjustment for age, sex, BMI, education, race/ethnicity, military service characteristics, and mental health conditions, only baseline posttraumatic stress disorder (PTSD) was significantly associated with risk of diabetes (odds ratio 2.07 [95% CI 1.31-3.29]). Deployments since September 2001 were not significantly related to higher diabetes risk, with or without combat exposure.

Conclusions: In this military cohort, PTSD symptoms at baseline but not other mental health symptoms or military deployment experience were significantly associated with future risk of self-reported diabetes.

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Figures

Figure 1
Figure 1
Co-occurrence of PTSD, panic, and depression among subjects at baseline.
See this image and copyright information in PMC

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References

    1. Hoge CW, Castro CA, Messer SC, McGurk D, Cotting DI, Koffman RL. Combat duty in Iraq and Afghanistan, mental health problems, and barriers to care. N Engl J Med 2004;351:13–22 - PubMed
    1. Mezuk B, Eaton WW, Albrecht S, Golden SH. Depression and type 2 diabetes over the lifespan: a meta-analysis. Diabetes Care 2008;31:2383–2390 - PMC - PubMed
    1. Cosgrove MP, Sargeant LA, Griffin SJ. Does depression increase the risk of developing type 2 diabetes? Occup Med (Lond) 2008;58:7–14 - PubMed
    1. Goodwin RD, Davidson JR. Self-reported diabetes and posttraumatic stress disorder among adults in the community. Prev Med 2005;40:570–574 - PubMed
    1. Black PH. The inflammatory consequences of psychologic stress: relationship to insulin resistance, obesity, atherosclerosis and diabetes mellitus, type II. Med Hypotheses 2006;67:879–91 - PubMed

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