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. 1984;6(4):509-12.
doi: 10.1016/0197-0186(84)90122-0.

Effects of stress on release of dopamine and serotonin in the striatum of spontaneously hypertensive rats: an in vivo voltammetric study

M Ikeda  1 , Y Hirata, K Fujita, M Shinzato, H Takahashi, S Yagyu, T Nagatsu
Affiliations

Effects of stress on release of dopamine and serotonin in the striatum of spontaneously hypertensive rats: an in vivo voltammetric study

M Ikeda et al. Neurochem Int. 1984.

Abstract

By use of in vivo voltammetry technique, in vivo release of dopamine and serotonin in the striatum under stress was found to be more prominent in spontaneously hypertensive rats (SHR) at 4 weeks of age than in control Wistar-Kyoto rats (WKY). Simultaneously, a greater activation of tyrosine hydroxylase in the striatum was demonstrated in SHR than in WKY. These results indicate that SHR is more susceptible to stress in the central monoaminergic neurons than WKY.

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