doi: 10.1073/pnas.75.2.955.
Antibody response of mice to chemically induced tumors
- PMID: 204940
- PMCID: PMC411377
- DOI: 10.1073/pnas.75.2.955
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Antibody response of mice to chemically induced tumors
Proc Natl Acad Sci U S A.
1978 Feb.
Abstract
BALB/c mice immunized with syngeneic methylcholanthrene-induced fibrosarcomas did not have antibodies against the unique tumor-specific transplantation antigens, even though they were capable of rejecting a lethal dose of tumor cells. Endogenous murine leukemia virus antigens expressed by certain of the tumors did, however, elicit high titers of antibodies, accounting for serological crossreactions that occurred between those tumors.
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