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. 1978 Feb;75(2):955-8.
doi: 10.1073/pnas.75.2.955.

Antibody response of mice to chemically induced tumors

J P Brown, J M Klitzman, I Hellström, R C Nowinski, K E Hellström

Antibody response of mice to chemically induced tumors

J P Brown et al. Proc Natl Acad Sci U S A. 1978 Feb.

Abstract

BALB/c mice immunized with syngeneic methylcholanthrene-induced fibrosarcomas did not have antibodies against the unique tumor-specific transplantation antigens, even though they were capable of rejecting a lethal dose of tumor cells. Endogenous murine leukemia virus antigens expressed by certain of the tumors did, however, elicit high titers of antibodies, accounting for serological crossreactions that occurred between those tumors.

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References

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