Comment on

• Odanacatib, a cathepsin-K inhibitor for osteoporosis: a two-year study in postmenopausal women with low bone density.

  Bone HG, McClung MR, Roux C, Recker RR, Eisman JA, Verbruggen N, Hustad CM, DaSilva C, Santora AC, Ince BA. Bone HG, et al. J Bone Miner Res. 2010 May;25(5):937-47. doi: 10.1359/jbmr.091035. J Bone Miner Res. 2010. PMID: 19874198 Clinical Trial.
• Two doses of sclerostin antibody in cynomolgus monkeys increases bone formation, bone mineral density, and bone strength.

  Ominsky MS, Vlasseros F, Jolette J, Smith SY, Stouch B, Doellgast G, Gong J, Gao Y, Cao J, Graham K, Tipton B, Cai J, Deshpande R, Zhou L, Hale MD, Lightwood DJ, Henry AJ, Popplewell AG, Moore AR, Robinson MK, Lacey DL, Simonet WS, Paszty C. Ominsky MS, et al. J Bone Miner Res. 2010 May;25(5):948-59. doi: 10.1002/jbmr.14. J Bone Miner Res. 2010. PMID: 20200929