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Randomized Controlled Trial
. 2011 May;283(5):1011-4.
doi: 10.1007/s00404-010-1516-z. Epub 2010 May 25.

Umbilical cord blood acid-base and gas analysis after early versus delayed cord clamping in neonates at term

Affiliations
Randomized Controlled Trial

Umbilical cord blood acid-base and gas analysis after early versus delayed cord clamping in neonates at term

Catalina De Paco et al. Arch Gynecol Obstet. 2011 May.

Abstract

Objective: To compare umbilical cord acid-base status and blood gas analysis between umbilical cords clamped within 10 s and at 2 min of delivery.

Methods: A total of 158 healthy full-term mothers were randomly assigned to an early clamping (<10 s post-delivery, n = 79) or delayed clamping (2 min post-delivery, n = 79) group. After application of inclusion criteria, umbilical vein blood acid-base status and gases were analyzed in 65 early clamped and 51 delayed clamped cords. Fewer cases could be examined in the umbilical artery: 55 cords in the early clamping group and 44 in the delayed one.

Results: Acid-base and gas analysis results did not significantly differ between the groups in the umbilical vein or umbilical artery, with the exception of a higher (p < 0.001) mean umbilical artery pO(2) value in the delayed versus early clamping group. No significant differences in umbilical vein or artery pCO(2) or HCO(3) (-) values were observed between the early and delayed clamp groups.

Conclusions: A delay of 2 min before umbilical cord clamping does not significantly change acid-base and gas analysis results, with the exception of a higher mean umbilical artery pO(2) value in the delayed clamping group.

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