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. 2010 Jul;51(4):499-503.
doi: 10.3349/ymj.2010.51.4.499.

Gender difference in patients with recurrent neurally mediated syncope

Jungwae Park  1 , Shin Yi Jang, Hye Ran Yim, Young Keun On, June Huh, Dae-Hee Shin, Jun Hyung Kim, June Soo Kim
Affiliations

Gender difference in patients with recurrent neurally mediated syncope

Jungwae Park et al. Yonsei Med J. 2010 Jul.

Abstract

Purpose: The gender difference of neurally mediated syncope is not well defined in a large patient population. The aim of this study was to evaluate the gender difference of clinical manifestations in patients with neurally mediated syncope who underwent head-up tilt test.

Materials and methods: The medical records of 1,051 consecutive patients with two or more episodes of syncope, who were diagnosed as having neurally mediated syncope by head-up tilt test, were retrospectively reviewed.

Results: Of 1,051 patients, 497 (47.3%) patients were male and 554 (52.7%) patients were female. Female patients were experiencing syncopal episodes for longer periods of their lives (8.2 +/- 9.5 years vs. 6.8 +/- 9.2 years, p = 0.002) and more episodes of syncope prior to head-up tilt test (HUT) (7.2 +/- 9.4 vs. 5.0 +/- 6.4, p = 0.001) than male patients. Micturition syncope (20.0 % vs. 5.2 %, p < 0.001) was observed more frequently in male patients than in female patients. To the contrary, however, defecation syncope (16.3 % vs. 9.3 %, p < 0.001) was observed more frequently in female patients than in male patients.

Conclusion: Female patients were experiencing syncopal episodes for longer periods of their lives and more episodes of syncope than male patients. Gender difference was also noted with regard to frequency of situational syncope.

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Conflict of interest statement

The authors have no financial conflicts of interest.

Figures

Fig. 1
Fig. 1
Distribution of age of first syncopal episode in 1,051 patients with recurrent neurally mediated syncope, expressed as proportions per 5-year bin of the total.
Fig. 2
Fig. 2
Distribution of time intervals between first and last syncopal episodes in 1,051 patients with recurrent neurally mediated syncope.
See this image and copyright information in PMC

References

    1. Soteriades ES, Evans JC, Larson MG, Chen MH, Chen L, Benjamin EJ, et al. Incidence and prognosis of syncope. N Engl J Med. 2002;347:878–885. - PubMed
    1. Ganzeboom KS, Colman N, Reitsma JB, Shen WK, Wieling W. Prevalence and triggers of syncope in medical students. Am J Cardiol. 2003;91:1006–1008. - PubMed
    1. Lipsitz LA, Wei JY, Rowe JW. Syncope in an elderly, institutionalised population: prevalence, incidence, and associated risk. Q J Med. 1985;55:45–54. - PubMed
    1. Savage DD, Corwin L, McGee DL, Kannel WB, Wolf PA. Epidemiologic features of isolated syncope: the Framingham Study. Stroke. 1985;16:626–629. - PubMed
    1. Grubb BP. Pathophysiology and differential diagnosis of neurocardio-genic syncope. Am J Cardiol. 1999;84:3Q–9Q. - PubMed