Science to practice: Can diffusion-weighted MR imaging findings be used as biomarkers to monitor the progression of renal fibrosis?
- PMID: 20501704
- DOI: 10.1148/radiol.100211
Science to practice: Can diffusion-weighted MR imaging findings be used as biomarkers to monitor the progression of renal fibrosis?
Abstract
In an experimental murine model of unilateral ureteral obstruction, Togao et al demonstrated that diffusion-weighted (DW) magnetic resonance (MR) imaging can depict and enable monitoring of abnormal changes in the progression of renal fibrosis; because these microstructural changes are complex and multifactorial, future studies focused on their specificity should be performed before they are applied in clinical trials.
Comment on
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Assessment of renal fibrosis with diffusion-weighted MR imaging: study with murine model of unilateral ureteral obstruction.Radiology. 2010 Jun;255(3):772-80. doi: 10.1148/radiol.10091735. Epub 2010 Apr 20. Radiology. 2010. PMID: 20406881 Free PMC article.
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