doi: 10.4103/0250-474X.58165.
Polyelectrolyte Complexes: A Review of their Applicability in Drug Delivery Technology
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- PMID: 20502564
- PMCID: PMC2866337
- DOI: 10.4103/0250-474X.58165
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Polyelectrolyte Complexes: A Review of their Applicability in Drug Delivery Technology
Indian J Pharm Sci.
2009 Sep.
Abstract
Over the past several years, great advances have been made towards novel drug delivery systems. The phenomena of interpolymer interactions and formation of polyelectrolyte complexes have been the focus of intensive fundamental and applied research. Interpolyelectrolyte complexes combine unique physicochemical properties with high biocompatibility. Studies have been carried out on many different polymer blends and types. Such combinations may possess unique properties that are different from those of individual component. The present review emphasizes on the applicability of polyelectrolyte complexes in drug delivery technology.
Keywords: Polyelectrolyte complex; drug delivery; electrostatic interaction; polyion; polymer.
Figures
Schematic representation of the formation and aggregation of PECs (a) Primary complex formation (b) Formation process within intracomplexes (c) Inter complex aggregation process
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