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. 1991 Jul;59(7):2502-4.
doi: 10.1128/iai.59.7.2502-2504.1991.

Somnogenic activity of pseudomurein in rabbits

L Johannsen  1 , H Labischinski, J M Krueger
Affiliations

Somnogenic activity of pseudomurein in rabbits

L Johannsen et al. Infect Immun. 1991 Jul.

Abstract

Pseudomurein is a major cell wall component of some archaebacteria that chemically differs from but morphologically, functionally, and structurally resembles eubacterial peptidoglycan. Eubacterial cell wall components, e.g., peptidoglycan, induce changes in sleep and body temperature. We now report that intravenous injections of rabbits with a suspension of pseudomurein from Methanobacterium thermoautotrophicum also induce similar central nervous system effects.

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