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. 2010 Jun;16(6):976-9.
doi: 10.3201/eid1606.091187.

Vaccinia virus infection in monkeys, Brazilian Amazon

Jônatas S Abrahão  1 , André T Silva-Fernandes, Larissa S Lima, Rafael K Campos, Maria I M C Guedes, Marcela M G Cota, Felipe L Assis, Iara A Borges, Milton F Souza-Júnior, Zélia I P Lobato, Cláudio A Bonjardim, Paulo C P Ferreira, Giliane S Trindade, Erna G Kroon
Affiliations

Vaccinia virus infection in monkeys, Brazilian Amazon

Jônatas S Abrahão et al. Emerg Infect Dis. 2010 Jun.

Abstract

To detect orthopoxvirus in the Brazilian Amazon, we conducted a serosurvey of 344 wild animals. Neutralizing antibodies against orthopoxvirus were detected by plaque-reduction neutralizing tests in 84 serum samples. Amplicons from 6 monkey samples were sequenced. These amplicons identified vaccinia virus genetically similar to strains from bovine vaccinia outbreaks in Brazil.

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Figures

Figure
Figure
Consensus bootstrap phylogenetic trees based on nucleotide sequences of orthopoxvirus vaccinia growth factor (vgf) (A) and hemagglutinin (ha) (B) genes. Trees were constructed with ha or vgf sequences by using the neighbor-joining method with 1,000 bootstrap replicates and the Tamura 3-parameter model in MEGA version 3.1 software (www.megasoftware.net). Bootstrap values >40% are shown. Nucleotide sequences were obtained from GenBank. Black dots indicate vaccinia virus (VACV) obtained from Cebus apella (VACV-TO CA) and Allouata caraya (VACV AC). All vgf sequences obtained from monkey serum samples showed 100% and are represented as a unique sequence in the vgf tree (VACV TO). HSPV, horsepoxvirus; VARV, variola virus; CPXV, cowpoxvirus; MPXV, monkeypoxvirus.
See this image and copyright information in PMC

Comment in

  • Whence feral vaccinia?
    Condit RC. Condit RC. Emerg Infect Dis. 2010 Jun;16(6):1022. doi: 10.3201/eid1606.100315. Emerg Infect Dis. 2010. PMID: 20507763 Free PMC article. No abstract available.

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