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. 2009 Dec;39(4):362-4.
doi: 10.4997/jrcpe.2009.425.

Statins: in the beginning

K S Lyons  1 , M Harbinson
Affiliations

Statins: in the beginning

K S Lyons et al. J R Coll Physicians Edinb. 2009 Dec.

Abstract

Since the first human trial of a hydroxymethylglutaryl-coenzyme A (HMG CoA) reductase inhibitor in 1978, the growth in importance of this drug class, both financially and medically, has been staggering. The aim of this paper is to summarise how this drug class was developed, highlighting the role ofAkira Endo.

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