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Comment
. 2010 May 28;32(5):583-5.
doi: 10.1016/j.immuni.2010.05.006.

PU.1 takes control of the dendritic cell lineage

Miriam Merad  1
Affiliations
Free article
Comment

PU.1 takes control of the dendritic cell lineage

Miriam Merad. Immunity. .
Free article

Abstract

Despite the importance of the cytokine receptor flt3 in dendritic cell (DC) homeostasis, little is known about its regulation during DC development. In this issue of Immunity, Carotta et al. (2010) reveal that the transcription factor PU.1 controls Flt3 expression in hematopoietic progenitors in a dose-dependent manner.

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