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Comment
. 2010 May 28;32(5):585-7.
doi: 10.1016/j.immuni.2010.04.014.

TGF-Beta to the rescue

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TGF-Beta to the rescue

Ethan M Shevach. Immunity. .
Free article

Abstract

Is transforming growth factor-beta (TGF-beta) required for induction of the transcription factor Foxp3 in developing thymocytes? Ouyang et al. (2010) demonstrate that TGF-beta in the thymus prevents deletion of Foxp3(+) regulatory T cells.

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