Wrapping up stereocilia rootlets
- PMID: 20510920
- DOI: 10.1016/j.cell.2010.05.022
Wrapping up stereocilia rootlets
Abstract
The actin-filled stereocilia of cochlear hair cells deflect in response to sound by pivoting around rootlets at their insertion points at the sensory cell surface. Kitajiri et al. (2010) now show that the actin-binding protein TRIOBP tightly bundles the actin filaments into rootlets, endowing these stereocilia "pivots" with unique elasticity and robustness.
Copyright 2010 Elsevier Inc. All rights reserved.
Comment on
-
Actin-bundling protein TRIOBP forms resilient rootlets of hair cell stereocilia essential for hearing.Cell. 2010 May 28;141(5):786-98. doi: 10.1016/j.cell.2010.03.049. Cell. 2010. PMID: 20510926 Free PMC article.
Publication types
LinkOut - more resources
Full Text Sources