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Case Reports
. 2010 Jun 1:10:246.
doi: 10.1186/1471-2407-10-246.

Primary myxofibrosarcoma of the parotid: case report

Xu Li  1 , Xin Chen, Zhao-Hui Shi, Yang Chen, Jing Ye, Li Qiao, Jian-Hua Qiu
Affiliations
Case Reports

Primary myxofibrosarcoma of the parotid: case report

Xu Li et al. BMC Cancer. .

Abstract

Background: Myxofibrosarcoma is common in the extremities of elderly people and is characterized by a high frequency of local recurrence.

Case presentation: We report a 37 year old female who presented with a 4-month history of facial pain and a 3-month history of painful progressive swelling in the preauricular area. She underwent a total parotidectomy. The tumor was histopathologically and immunohistochemically diagnosed as a low-grade myxofibrosarcoma. The patient was free of disease 9 months after surgery with uneventful post-operative clinical course.

Conclusions: Parotid area swelling should always alert doctors. To our knowledge, this is the first case of parotid myxofibrosarcoma. It should be added to the differential diagnosis of diseases of the parotid. We have to recognize this disease and seek adequate treatment for it.

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Figures

Figure 1
Figure 1
CT scan of the patient. A contrast enhanced Computed tomography (CT) scan revealed a well defined soft tissue mass (40 mm × 25 mm, arrow) in the right deep parotid lobe.
Figure 2
Figure 2
Relationship between tumor and facial nerve represented during surgery. The tumor was a grayish-red collagenous mass (black arrow). Main stem of the facial nerve (yellow arrow) was involved.
Figure 3
Figure 3
Photomicrograph of the tumor (H&E; ×100). Myxoid areas in association with spindle cells showing a pleomorphic storiform pattern as seen.
Figure 4
Figure 4
Positive immunohistochemical findings (immunoperoxidase technique; ×200). The tumor cells are positive for ACT (a) and VIM (b). Labeling index of Ki-67 (c) is 35%.
Figure 5
Figure 5
Negative immunohistochemical findings (immunoperoxidase technique; ×200). The tumor cells are negative for CD34 (a), DES (b), MG (c) and SMA (d).
See this image and copyright information in PMC

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