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Editorial
. 2010 Jul;56(1):31-3.
doi: 10.1161/HYPERTENSIONAHA.109.139758. Epub 2010 Jun 1.

Dissecting the complex physiology of endothelin: new lessons from genetic models

Editorial

Dissecting the complex physiology of endothelin: new lessons from genetic models

David M Pollock. Hypertension. 2010 Jul.
No abstract available

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Figures

Figure 1
Figure 1
Hypothetical scheme depicting the balance of ETA and ETB receptors in the vascular wall.

Comment on

References

    1. Yanagisawa M, Kurihara H, Kimura S, Tomobe Y, Kobayashi M, Mitsui Y, Yazaki Y, Goto K, Masaki T. A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature. 1988;332:411–415. - PubMed
    1. Gariepy CE, Williams SC, Richardson JA, Hammer RE, Yanagisawa H. Transgenic expression of the endothelin-B receptor prevents congenital intestinal aganglionosis in a rat model of Hirschsprung disease. J Clin Invest. 1998;102:1092–1101. - PMC - PubMed
    1. Gariepy CE, Cass DT, Yanagisawa M. Null mutation of endothelin receptor type B gene in spotting lethal rats causes aganglionic megacolon and white coat color. Proc Natl Acad Sci U S A. 1996;93:867–872. - PMC - PubMed
    1. Kirkby NS, Hadoke PW, Bagnall AJ, Webb DJ. The endothelin system as a therapeutic target in cardiovascular disease: great expectations or bleak house? Br J Pharmacol. 2008;153:1105–1119. - PMC - PubMed
    1. Pollock DM, Pollock JS. Evidence for endothelin involvement in the response to high salt. Am J Physiol Renal Physiol. 2001;281:F144–150. - PubMed

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