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. 2010 Aug;37(4):299-300.
doi: 10.1111/j.1744-313X.2010.00922.x. Epub 2010 May 27.

A discrepancy between serological and molecular typing results led to identification of a novel HLA-B*57 allele: HLA-B*5728N

E Cosentini  1 , S Frison, E Longhi, M Mantovani, V Luongo, G Ciardiello, P Bruno, F Poli
Affiliations

A discrepancy between serological and molecular typing results led to identification of a novel HLA-B*57 allele: HLA-B*5728N

E Cosentini et al. Int J Immunogenet. 2010 Aug.

Abstract

Summary Here, we describe the characterisation of a new allelic variant of HLA-B*57. The novel allele, HLA-B*5728N, was identified with sequence-based typing in a Caucasoid family. HLA-B*5728N, differs from HLA-B*5701 because of a nucleotide substitution at position 420 (C->G) resulting in a coding change from Tyrosine to a stop codon.

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