Comment
doi: 10.1016/j.cmet.2010.05.006.
Autophagy: a potential link between obesity and insulin resistance
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- PMID: 20519116
- DOI: 10.1016/j.cmet.2010.05.006
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Comment
Autophagy: a potential link between obesity and insulin resistance
Cell Metab.
.
Abstract
Dysregulation of autophagy contributes to aging and to diseases such as neurodegeneration, cardiomyopathy, and cancer. The paper by Yang et al. (2010) in this issue of Cell Metabolism indicates that defective autophagy may also underlie impaired insulin sensitivity in obesity and that upregulating autophagy can combat insulin resistance.
Copyright 2010 Elsevier Inc. All rights reserved.
Comment on
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Defective hepatic autophagy in obesity promotes ER stress and causes insulin resistance.Cell Metab. 2010 Jun 9;11(6):467-78. doi: 10.1016/j.cmet.2010.04.005. Cell Metab. 2010. PMID: 20519119 Free PMC article.
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