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Comment
. 2010 Jun 9;11(6):449-51.
doi: 10.1016/j.cmet.2010.05.006.

Autophagy: a potential link between obesity and insulin resistance

Patrice Codogno  1 , Alfred J Meijer
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Free article
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Autophagy: a potential link between obesity and insulin resistance

Patrice Codogno et al. Cell Metab. .
Free article

Abstract

Dysregulation of autophagy contributes to aging and to diseases such as neurodegeneration, cardiomyopathy, and cancer. The paper by Yang et al. (2010) in this issue of Cell Metabolism indicates that defective autophagy may also underlie impaired insulin sensitivity in obesity and that upregulating autophagy can combat insulin resistance.

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