Chronic kidney disease and GWAS: "the proper study of mankind is man"
- PMID: 20519117
- DOI: 10.1016/j.cmet.2010.05.009
Chronic kidney disease and GWAS: "the proper study of mankind is man"
Abstract
Genome-wide association studies (GWAS) have been applied to complex diseases such as diabetes and hypertension, successfully uncovering strong gene associations of potential pathophysiologic significance. Recently, two studies (Köttgen et al., 2010; Chambers et al., 2010) have been applied to uncover genes relevant to the pathophysiology of chronic kidney disease (CKD).
Copyright 2010 Elsevier Inc. All rights reserved.
Comment on
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Genetic loci influencing kidney function and chronic kidney disease.Nat Genet. 2010 May;42(5):373-5. doi: 10.1038/ng.566. Epub 2010 Apr 11. Nat Genet. 2010. PMID: 20383145 Free PMC article.
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New loci associated with kidney function and chronic kidney disease.Nat Genet. 2010 May;42(5):376-84. doi: 10.1038/ng.568. Epub 2010 Apr 11. Nat Genet. 2010. PMID: 20383146 Free PMC article.
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