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. 2010 Aug;48(8):2965-7.
doi: 10.1128/JCM.02391-09. Epub 2010 Jun 2.

Isolation and detection of Campylobacter concisus from saliva of healthy individuals and patients with inflammatory bowel disease

Li Zhang  1 , Vanna Budiman, Andrew S Day, Hazel Mitchell, Daniel A Lemberg, Stephen M Riordan, Michael Grimm, Steven T Leach, Yazan Ismail
Affiliations

Isolation and detection of Campylobacter concisus from saliva of healthy individuals and patients with inflammatory bowel disease

Li Zhang et al. J Clin Microbiol. 2010 Aug.

Abstract

The presence of Campylobacter concisus in the saliva of healthy individuals and patients with inflammatory bowel disease (IBD) was examined. C. concisus was detected in 97% of the healthy individuals and 100% of the patients with IBD tested. The C. concisus culture positivity rate in younger children was significantly lower than that in the other age groups.

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Figures

FIG. 1.
FIG. 1.
Detection of C. concisus by culture and PCR (dotted column) in saliva samples from healthy individuals in different age groups. The C. concisus culture positivity rate of children 3 to 5 years old was significantly lower than that of the other age groups (P < 0.01 compared to the group of patients 12 to 18 years old and P < 0.05 compared to the remaining groups).
FIG. 2.
FIG. 2.
Comparison of the SDS-PAGE profiles of six oral C. concisus strains and a biopsy C. concisus strain isolated from a child with CD. Profile 1: five of the six oral C. concisus strains showed this pattern. Profile 2: one of the six oral C. concisus strains showed this pattern. Profile 3 is the pattern of a biopsy C. concisus strain from the same child who yielded the isolates with profiles 1 and 2. Protein bands a to c are common to one oral C. concisus strain and the biopsy strain from the same child. Lane M, molecular size markers.
See this image and copyright information in PMC

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