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. 1991 Jan 16;100(1):91-6.
doi: 10.1007/BF00230813.

Cerium depresses protein synthesis in cultured cardiac myocytes and lung fibroblasts

K Shivakumar  1 , R R Nair
Affiliations

Cerium depresses protein synthesis in cultured cardiac myocytes and lung fibroblasts

K Shivakumar et al. Mol Cell Biochem. .

Abstract

The present study examined the effect of Cerium on protein synthesis in cultured cardiac myocytes and lung fibroblasts exposed to normal and markedly subnormal levels of Mg2+. Cerium was found to have a general inhibitory effect on protein synthesis in these cell types, including the synthesis of myofibrillar proteins in the cardiac myocytes. Further, the effect of the metal ion was more pronounced in cells exposed to the Mg2(+)-deficient medium. The possible implications of the observations are discussed.

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References

    1. Circ Res. 1985 Jun;56(6):884-94 - PubMed
    1. J Biol Chem. 1981 May 25;256(10):4863-70 - PubMed
    1. Cell Biol Int Rep. 1985 Jan;9(1):51-60 - PubMed
    1. Trends Biochem Sci. 1988 Jan;13(1):15-9 - PubMed
    1. Proc Natl Acad Sci U S A. 1978 Sep;75(9):4379-83 - PubMed

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