Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2010 May;20(3):683-4.
doi: 10.1111/j.1750-3639.2010.00382.x.

20 year old lady with a paraspinal mass

Orna O'Toole  1 , Alan O'Hare, Liam Grogan, Ciaran Bolger, Francesca M Brett
Affiliations
Case Reports

20 year old lady with a paraspinal mass

Orna O'Toole et al. Brain Pathol. 2010 May.

Abstract

A 20 year old female presented with a 4 month history of right upper limb pain and paraesthesias. She had no systemic symptoms and no prior medical or family history of note. MRI revealed a right-sided intradural extramedullary mass extending from C7-T1 and displacing the spinal cord. While awaiting surgery her symptoms progressed to involve the right lower limb. She was re-imaged and the lesion now extended from C5 to T3 with spinal cord compression at C7-T1. The radiological features and recent rapid growth were felt to be in keeping with a large plexiform neurofibroma. The patient underwent emergency resection of the lesion and pathology revealed Hodgkin's Lymphoma (HL)-mixed cellularity type. A mediastinal mass was identified on further imaging and biopsy confirmed the diagnosis of HL-stage IV. The patient is currently undergoing treatment with ABVD chemotherapy. CNS-HL is extremely rare and may occur de novo or in association with systemic disease. Lesions may be parenchymal or dural based and are usually intracranial with an increased risk of CNS involvement in HL-mixed-cellularity type as in our patient. This is the first report in the literature of CNS-HL radiologically mimicking a paraspinal plexiform neurofibroma.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Figure 2
Figure 2
Figure 3
Figure 3
Figure 4
Figure 4
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

References

    1. Akyuz C, Yalcin B, Atahan IL et al (2005) Intracranial involvement in Hodgkin's disease. Pediatr Hematol Oncol 22:589–596. - PubMed
    1. Balsari KR, Kadri PA, Husain M et al (2005) Malignant lymphoma of the trigeminal region. Case illustration. J Neuro-oncol 73:279–280. - PubMed
    1. Cuttner J, Meyer R, Huang YP (1979) Intracerebral involvement in Hodgkin's disease: a report of 6 cases and review of the literature. Cancer 43(4):1479–506. - PubMed
    1. Figueroa BE, Brown JR, Nscimento A et al (2004) Unusual sites of Hodgkin's lymphoma: CASE 2. Hodgkin's lymphoma of the CNS masquerading as meningioma. J Clin Oncol 22:4228–4230. - PubMed
    1. Gerstner RG, Abrey LE, Schiff D et al (2008) CNS Hodgkin lymphoma. Blood 112:1658–1661. - PMC - PubMed

Publication types