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Review
. 2010:33 Suppl 5:2-11.
doi: 10.1159/000313971. Epub 2010 May 14.

[Current developments and perspectives in targeted therapies]

[Article in German]
Nicolas Dickgreber  1 , Rudolf M Huber, Martin Reck, Niels Reinmuth, Wolfgang Schütte, Monika Serke, Jürgen Wolf
Affiliations
Review

[Current developments and perspectives in targeted therapies]

[Article in German]
Nicolas Dickgreber et al. Onkologie. 2010.

Abstract

Many different approaches for improving the prognosis of patients with advanced non-small-cell lung cancer (NSCLC) are currently being investigated. This article discusses the significance of maintenance therapy after primary chemotherapy and reviews study data on second-generation epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs), inhibitors of insulin-like growth factor receptors (IGFR), vascular-disrupting agents (VDAs) and multi-TKIs of vascular endothelial growth factor receptors (VEGFR). The article also looks at the future prospects of using genetic markers in the field of NSCLC.

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